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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPK4
All Species:
3.33
Human Site:
T275
Identified Species:
7.33
UniProt:
P57078
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57078
NP_065690
832
91611
T275
G
D
P
R
V
R
P
T
F
Q
G
N
G
L
N
Chimpanzee
Pan troglodytes
XP_001134659
786
86619
V236
I
L
H
I
M
V
K
V
V
K
G
H
R
P
E
Rhesus Macaque
Macaca mulatta
XP_001107026
786
86655
V236
I
L
H
I
M
V
K
V
V
K
G
H
R
P
E
Dog
Lupus familis
XP_544897
826
90932
V276
K
N
I
L
H
I
M
V
K
V
V
K
G
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERK0
786
86594
V236
I
L
H
I
M
M
K
V
V
K
G
H
R
P
E
Rat
Rattus norvegicus
P0C8E4
606
67182
P99
L
Y
G
A
C
L
N
P
V
C
L
V
M
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511321
791
87316
K236
N
I
L
H
I
M
V
K
V
V
K
G
H
R
P
Chicken
Gallus gallus
XP_416738
789
87316
S250
E
L
P
A
V
S
K
S
R
P
H
S
C
N
N
Frog
Xenopus laevis
NP_001080415
720
79835
V213
D
V
Y
S
F
A
I
V
I
W
G
I
L
T
Q
Zebra Danio
Brachydanio rerio
Q502K3
1071
114412
T357
G
H
E
L
L
I
S
T
L
M
T
N
G
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001180763
1378
147477
I147
P
D
V
T
K
Y
L
I
S
Q
G
A
Q
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
92.6
83.2
N.A.
84.9
23
N.A.
77.5
72.1
61.6
22
N.A.
N.A.
N.A.
N.A.
21.4
Protein Similarity:
100
93.9
93.5
88.3
N.A.
89.3
38.9
N.A.
85.6
83.7
72.9
35.8
N.A.
N.A.
N.A.
N.A.
34.9
P-Site Identity:
100
6.6
6.6
6.6
N.A.
6.6
0
N.A.
0
20
6.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
26.6
26.6
13.3
N.A.
26.6
0
N.A.
6.6
33.3
6.6
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
10
0
0
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
10
0
0
% C
% Asp:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
28
% E
% Phe:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
19
0
10
0
0
0
0
0
0
0
55
10
28
0
0
% G
% His:
0
10
28
10
10
0
0
0
0
0
10
28
10
10
0
% H
% Ile:
28
10
10
28
10
19
10
10
10
0
0
10
0
0
0
% I
% Lys:
10
0
0
0
10
0
37
10
10
28
10
10
0
0
0
% K
% Leu:
10
37
10
19
10
10
10
0
10
0
10
0
10
10
0
% L
% Met:
0
0
0
0
28
19
10
0
0
10
0
0
10
0
0
% M
% Asn:
10
10
0
0
0
0
10
0
0
0
0
19
0
10
28
% N
% Pro:
10
0
19
0
0
0
10
10
0
10
0
0
0
28
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
10
% Q
% Arg:
0
0
0
10
0
10
0
0
10
0
0
0
28
10
10
% R
% Ser:
0
0
0
10
0
10
10
10
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
10
0
0
0
19
0
0
10
0
0
10
0
% T
% Val:
0
10
10
0
19
19
10
46
46
19
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _